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Description
Most GI symptoms peaked between weeks 4 and 10 and faded by week 12

When a peptide is close to its isoelectric point, where the overall charge is reduced, it may become less soluble and more likely to precipitate

The depletion of amino acids at baseline in ME/CFS, coupled with their impaired glucose metabolism, could limit the availability of alternative energy sources during exertion, potentially contributing to PEM

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Journal of Proteome Research 12 (6): 288594
