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Efficacy and safety of AXS05, a novel, oral, NMDAreceptor antagonist with multimodal activity, in agitation associated with Alzheimers disease: results from ADVANCE1, a phase 2/3, doubleblind, active and placebocontrolled trial: developments in clinical trials and cognitive assessment

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These findings imply that retromer binds cooperatively to both motifs for efficient LYSET recycling to the Golgi (Fig

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