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The B12 intravenous dose is usually the same as the intramuscular dose, from 1000 mcg to 2500 mcg per infusion

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Although the intracerebral injection looked efficient in some studies on animal models, it is also an invasive method

10.5483/BMBRep.2005.38.2.232 70 PolleA

Additionally, busulfan has been shown to accelerate the senescence process in murine bone marrow cells, thereby inhibiting their hematopoietic functions [68]
