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Once opened, the bottle should be kept refrigerated for a maximum of 1 month

While the causality of auto-Abs and autonomic disorders is not entirely elucidated, and likely varies depending on the infectious disease triggering the production of auto-Abs, one may postulate that removal of these auto-Abs may reduce the risk of autonomic disorder development

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Lifestyle factors and lumbar disc disease: results of a German multi-center case-control study (EPILIFT)
