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In addition, glutamine plays a role as the efflux solute for the import of leucine which supports glutamine to activate mTORC1 through glutaminolysis

Iron deficiency may contribute to compromised thyroid hormone synthesis, storage, and secretion due to decreased oxygen transport or by impairing heme-dependent thyroid peroxidase despite adequate iodine intake
doi: 10.1110/ps.0210802

In such cases, the focus should shift to investigating potential underlying causessuch as myeloproliferative disorders, liver disease, or renal dysfunctionrather than attributing symptoms to the elevated B12 itself

Early clinical trials (NCT01568099, NCT01885494, NCT02216188, NCT02618941, NCT02267434) of the -syn mimicking peptides PD01A (Volc et al
