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doi: 10.1007/s11306-019-1604-4

In dietinduced obese mice, NNMTi treatment significantly reduced liver weight, liver volume, and hepatic triglyceride levels, alleviated hepatic steatosis and inflammatory infiltration, downregulated inflammatory factors (such as TNF and IL6) and lipogenic genes (such as FAS), and upregulated lipolytic genes (such as ATGL) in the liver

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Yes, when administered by trained professionals, they are very safe with minimal side effects

For long-term storage (several months to years), vials may be placed in a freezer at approximately -80C (-112F)