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Low-dose lithium reduces NR2B subunit phosphorylation at the NMDA receptor, directly limiting calcium influx, and upregulates glutathione-dependent enzymes in animal models. Start at 5 mg daily
Similar to GPx, catalase converts hydrogen peroxide into water and oxygen, thus preventing the buildup of hydrogen peroxide and inhibiting the formation of highly reactive hydroxyl radicals (OH) via the Fenton reaction (101, 102)
doi: 10.1039/b408044k
