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This pH-dependent prediction is important to consider when attempting to predict absorption

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J Pharm Sci 97(4):15931605 Uys JD, Niesink RJ (2005) Pharmacological aspects of the combined use of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and gamma-hydroxybutyric acid (GHB): a review of the literature

Heavier individuals may need higher absolute doses to achieve equivalent tissue concentrations, while lighter individuals may find lower doses sufficient

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