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Description
Results Phenotypes of MC4R-deficient mice MC4R KO mice showed a significant increase in body weight, food intake, fat mass, and lean mass compared with those in normal mice
Pairing them with Tesamorelin or CJC-1295/Ipamorelin preserves and builds lean tissue while the GLP-1 handles fat reduction, resulting in better body composition than either approach alone

10.1038/nsmb.1577

There is extensive published research on GLP-1/GIP medicines in weight-management settings

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