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Microglia can be activated by cell-surface receptors for endotoxin, cytokines, chemokines, misfolded proteins, serum factors and ATP (Figure 1.6)

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All measurements include a 3-minute mix, allowing the probe to retract and collapse the transient micro chamber

Overall, microbially produced metabolites act as potent CNS regulators, either by modulating the vagus signaling and systemic immunity or by directly crossing the BBB ( 3.7.4 Radiation-induced injuries and microbial mediation Radiation-induced injuries initiate local and systemic responses, which are closely related to the gut microbiome's integrity

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