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doi: 10.1016/j.blre.2014.10.003 [DOI] [PMC free article] [PubMed] [Google Scholar] 160.O-o O-A, Page MJ, Soma P, Pretorius E

Compared to the WT USP2, USP2 K447R transfection suppressed TGF1-mediated upregulation of USP2 lactylation, which was not further affected by SIRT2 OE (Fig

The biological importance of these post-transcriptional modifications has emerged during the last decade since diseases such as cancers or neurological disorders have been linked to the dysfunction of RNA-modifying enzymes (or writers ( The most frequent RNA epitranscriptomic marks are methylation either on the RNA bases or on the 2-OH group of the ribose

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