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Preclinical studies using T4 (including the RGN-259 ophthalmic clinical trials) have not identified significant adverse events at therapeutic doses

All of these people making black market peptides and GLP1s and marketing direct to our consumers and violating patent laws and infringing upon these pharmaceutical companies

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Subsequent work by Heffernan and coworkers (2001) confirmed the peptides effects in obese mouse models, with chronic administration associated with reduced body weight gain and decreased adiposity without concurrent changes in food intake