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Because they are not able to metabolize the acetaldehyde, Oriental Asians with the ALDH2 allele feel sick when they drink ethanol
Zha W., Wang J., Guo Z., et al., Efficient Delivery of VEGFA mRNA for Promoting Diabetic Wound Healing via Ionizable Lipid Nanoparticles, International Journal of Pharmaceutics 632 (2023): 122565
MAO, present in the outer mitochondrial membrane, and -ketoglutarate dehydrogenase (-KGDH), the TCA cycle enzyme complex, are able to generate H 2 O 2
In times of energy demand, the breakdown of lipid droplets through lipophagy provides fatty acids for mitochondrial oxidation
Zanichelli V, Sharland M, Cappello B et al (2023) The WHO aware (Access, Watch, Reserve) antibiotic book and prevention of antimicrobial resistance
