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It depends on: Compound solubility (hydrophilic vs

An integrated pathway based on in vitro data for the human hazard assessment of nanomaterials

When GABA binds to these receptors at post-synaptic sites, the ion channel opens, enabling the influx of chloride (Cl ) ions into the cell along a concentration gradient resulting in a change in the membrane potential

This process helps prevent the accumulation of these reactive molecules, which can damage cellular structures
