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Skipping sun protection UV exposure on freshly treated skin is the leading cause of post-treatment hyperpigmentation, particularly for Fitzpatrick IV through VI skin tones

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Ferroptosis suppressor protein 1 (Fer1) downregulates the expression of Nrf2/HO-1, chelates unstable Fe2+ in the iron pool, decreases free iron concentration, and inhibits ferroptosis, improving symptoms in colitis patients and DSS-induced colitis in mice [264, 290]

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Hence, efforts have been devoted to exploring supplements capable of enhancing intestinal health [77]

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Centre for Clinical Practice at NICE (UK)

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To further validate the role of DT-109 in SMC phenotype conversion, we conducted in vitro experiments using ox-LDL-treated HASMC and A7r5 cells

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