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Description
Zinc plays an important role in many biological processes, and it is required for enzyme function, nucleic acid synthesis, and as a cofactor in many proteins (159162)
Complete loss of neurofibromin activity, caused by second hit mutations, leads to hyperactivation of Ras signaling and tumor onset
OncoTargets Therapy
Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter
doi: 10.1002/1098-1136(20010315)33:4 3.0.CO;2-N 92 DerisbourgM.LeghayC.ChiappettaG.Fernandez-GomezF.-J.LaurentC.DemeyerD.et al
