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doi: 10.1124/jpet.116.239509 57

Choi JE, Villarreal J, Lasala J, Gottumukkala V, Mehran RJ, Rice D, Yu J, Feng L, Cata JP

The characterization of neuroinflammation is carried out by the activation of microglia and the release of pro-inflammatory cytokines

Taylor, B.A., Vaccaro A.R.., Hilibrand, A.S., Zlotolow, D.A., Albert, T.J.: The Risk of Foraminal Violation and Nerve Root Impingement After Anterior Placement of Lumbar Interbody Fusion Cages

This certainly carries some risk, as the occurrence of any potential adverse effects will not immediately be linked to the supplement by the patient or by the healthcare professional