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A further 8 pK a values for Alloxydim analogues were also obtained from the literature (Supplementary Table 1)

(11;12) Neither article clearly identified the studies on which the CCCDTD recommendation was based, nor how the recommendation was determined to be Grade B, Level 2

It may exclude the necessity of subsequent invasive investigations

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Oncogenic PIK3CA increases the dependency of cancer cells on glutamine by upregulating the expression of mitochondrial GPT2, which catalyzes the transamination reaction that converts glutamate and pyruvate into -KG and alanine 175