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(ref 16), Nelson and De Ligny (ref 19) and Korenman and Arefeva (ref 31,34) are markedly higher, sometimes by an order of magnitude, than other results and are therefore rejected

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Instead, we took advantage of three amino acid substitutions (E505Q, T527M, and K573P

Univariate logistic regression adjusted for time from symptoms onset and thrombolysis administration was used to study the association of extracted features with recanalization success, hemorrhagic transformation (HT) or both (bad outcome)