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Aging-related induction of inducible nitric oxide synthase is vasculo-protective to the arterial media

2025;85(12):2287-2302.e9

Beginning at 4 days after doxycycline addition, we observed a gradual decline in RER, demonstrating a shift towards increased lipid oxidation (Fig 2A)

Finally, binding of PLC to c-MET results in the activation of protein kinase C (PKC), which can then negatively regulate c-MET receptor phosphorylation and activity [Gandino et al
