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Support as usual Participants allocated to support as usual receive usual care only

Once delivered, bFGF attenuated oxidative stress through regulation of apoptosis-related protein expression and activation of the PI3K/AKT/Nrf2 signaling pathway, thereby reducing neuronal apoptosis induced by repeated ischemia-reperfusion and ultimately ameliorating cognitive impairment in VD mice

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However, because the lactic acid makes the skin more sensitive to the sun, its best to use it at night