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Description
and KPV (10mg), a three-amino-acid fragment from the C-terminal region of alpha-melanocyte-stimulating hormone

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Pitolisant's efficacy could be mediated through its activity that increases the synthesis and release of histamine in the brain via competitive binding to presynaptic histamine-3 autoreceptors

KPV is a fragment of a larger peptide, alpha-melanocyte stimulating hormone (a-MSH) which is produced naturally in the pituitary gland

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