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Matrine induces ferroptosis in cervical cancer through activation of piezo1 channel

We then compared the activities of ACO2 and the Fe-S cluster dependent respiratory complexes and observed that in contrast to cystine starvation, the functions of these proteins decay within 16 h of DFO treatment or NFS1 or ISCU knockdown (Fig

Pharmacological activity and action mechanisms of milk thistle and silymarin on pancreatic cancer It has been shown that silibinin inhibits the proliferation of pancreatic cancer cells due to the induction of G1 phase cell cycle arrest and increase in the expression of cyclin-dependent kinase inhibitor (p15 INK4B ) (63)

This classification is also in accordance with the in vivo data, as all three isothiocyanates have been found to be strong or extreme contact sensitizers in the LLNA
