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doi: 10.1371/journal.pone.0123454

Furthermore, entacapone combined with imatinib, a kind of TKIs, for leukemia treatment completed phase I clinical trials in 2022, highlighting its potential as a therapeutic enhancer in clinical settings (NCT04006769)

doi: 10.1016/j.actbio.2022.04.045 31 JassalMBoominathanVPFerreiraTSenguptaSBhowmickS

Microbial metabolism proceeds through a biphasic process: bacterial glycosidases initially catalyze deglycosylation to liberate aglycones, followed by ring-fission and reduction reactions generating diverse phenolic acids and derivatives (243)

Homogenous refinement as implemented in cryoSPARC resulted in ~7.4 resolution map according to gold standard Fourier Shell Correlation (FSC)