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DCs comprise multiple subsets with distinct functions but can be broadly classified into two major subsets, myeloid DCs [including classical/conventional DCs (cDCs), which are further subdivided into classical type 1 DCs (cDC1s) and classical type 2 DCs (cDC2s), monocyte-derived DCs (MoDCs), and Langerhans cells] and plasmacytoid DCs (pDCs) ( in vivo : Flt3-L supports the development of cDCs and pDCs derived from bone marrow (BM) precursors, whereas GM-CSF contributes to the development of MoDCs, as well as inflammation-induced myeloid DCs ( Figure 1 )

The relationship between the timing of sleep and the circadian phase (as estimated by a circadian marker) can be quantified by the time interval (phase angle) between the two rhythms

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These include energy production, the synthesis and breakdown of fatty acids, and creating other essential compounds

DMSO (-) was used as a control treatment