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For a fuller walk-through of pre- and post-mixing storage, see the guide on how to store peptides before and after reconstitution
After gastric bypass surgery, the smaller stomach produces less intrinsic factor, and the shortened digestive tract has less opportunity to absorb B12 as food passes through it

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Evidence from a Molecular Pharmaceutics study shows acetate counterions can become part of peptide aggregates, so the acid plays a real role in solution behavior, but at the diluted concentrations used in reconstitution it primarily serves to keep the peptide clear and in solution

The primary reason B12 status can decline after gastric banding is reduced intake and tolerance of B12-rich foods
