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Perhaps by influencing inflammatory, metabolic, or immune pathways involved in cancer development

This has been more thoroughly documented for large proteins than for small peptides

10.3390/plants13162215 51 HuangC

Epidermal growth factor receptor mediated signal transduction pathway Epidermal growth factor receptor (EGFR) is a cell surface signaling protein that plays an essential role in stimulating cell proliferation and evading apoptosis

[24] That observation is quietly profound for this articles theme: even in intact human physiology, local IGF-1 signaling can carry much of the growth load while circulating, protein-bound IGF-1 is dramatically reduced, which is exactly the local matters logic that made the MGF splice variant interesting in the first place