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These findings suggested that busulfan can significantly induce ROS creation and reduce antioxidants, leading to oxidative stress and lipid peroxidation in testicular tissue, which, in turn, can result in germ cell death, spermatogenesis impairment, and infertility (49)
Cutaneous xerosis affects more than 15% of patients receiving targeted treatment [42]
Studies in aged rats show that mitochondrial membrane potential, cardiolipin content, respiratory control ratio, and cellular oxygen uptake are significantly reduced compared to young animals, while oxidative stress markers are elevated
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Diagnostic Modalities in Heart Failure: A Narrative Review Cureus doi: 10.7759/cureus.67432 Hegazy Y, Chung M, Zamora N, Lee HA, Ghallab M
