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doi: 10.1038/bjc.2013.809 40 LiuSChengC

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Supported by the National Natural Science Foundation of China (NSFC 21365013), Social Science Planning Project of Jiangxi Province (19WT94) and the Key Lab of Aquatic Training Monitoring and Intervention of General Administration of Sport of China (No

Hormonal fluctuations increase oxidative stress Stress and disrupted sleep deplete antioxidant reserves Alcohol and caffeine intake often rise Low-grade inflammation becomes more common Exercise recovery demands greater antioxidant support Studies show that glutathione levels are significantly lower in postmenopausal women. This means antioxidant capacity is already reduced before additional stressors are added

The single published human case series and unpublished clinical trial data provide preliminary safety reassurance but insufficient evidence for clinical efficacy claims