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In iron metabolism, to block iron entry into the brain, knockdown of Nrf2 reduces FPN expression on BMECs and may serve as a means to avoid brain iron overload (Han et al

Therefore, monitoring platinum in the ultrafiltrate rather than in the plasma is an accepted strategy to control oxaliplatin metabolism

This phenolic compound has been shown to help with insulin sensitivity and even help with protecting nerve cells from damaging stress (10)

Despite the fact that the dose-limiting adverse effect of oxaliplatin is mainly peripheral neurotoxicity and not, like in case of cisplatin, nephrotoxicity, also for oxaliplatin oxidative damage in the kidney has been described 48

Furthermore, in jurisdictions where certain probiotics are regulated as prescription medications, consultation with a physician or a clinically trained pharmacist is imperative (517)