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Rapid endothelial restoration and activation of the major collaterals (in addition, there are abundant anastomoses between individual vessels on both surfaces of the large intestine (Kachlik, et al., 2010)) may reorganize blood flow (Vukojevic et al., 2018

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Blood lactate concentrations begin to fall within about 15-30 minutes following oral or parenteral dosing and are a useful biomarker of DCA's action on PDC

doi: 10.1038/84818

Chronic neuroinflammation, driven by the activation of microglia and astrocytes, also plays a pivotal role in AD progression
