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In an animal study, dietary betaine supplementation was found to limit obesity via inhibiting new white adipose tissue formation, enhancing lipid metabolism through increasing mitochondrial biogenesis and also improved insulin resistance ( NAFLD is associated with insulin resistance

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doi: 10.1016/s0006-3223(02)01741-9

Nevertheless, Mildronate also promotes metabolic switch to more efficient glucose utilization, which may be advantageous in conditions of ischemia or increased exercise [4]

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