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Description
The Ure2 class is composed of TmGst1, TmGst2, TmGst3, TmGst10, and TmGst15

[DOI] [PMC free article] [PubMed] [Google Scholar] 241.Ilic S., Drmic D., Franjic S., Kolenc D., Coric M., Brcic L., Klicek R., Radic B., Sever M., Djuzel V., et al

Moreover, LNA043 is currently being investigated in clinical trials for the treatment of articular cartilage lesions (NCT03275064) and knee osteoarthritis (NCT04864392, NCT04814368)

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Thanks to the water molecules at the edge having less freedom to move, this region tends to be the first to freeze