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Description
Taken together, these data reveal that IAV- infected DC significantly increase glycolysis without increased shuttling of acetyl CoA from pyruvate into the TCA cycle, while also improving their capacity and flexibility for mitochondrial substrate oxidation, including markedly increasing glutaminolysis
The mechanisms of cellular uptake were explored by addition of free targeting ligands, endocytic and metabolic inhibitors, co-localization of nanocarriers with intracellular organs, and surface charge modification of cells
BurnimMPutchaNLaFonDWooHAzarAGroenkeLet al
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PubMed 11121901.
