glutathione decreases with age Changes in levels of the antioxidant in brain and blood across the span of healthy adults: A systematic review What Is Glutathione? — Purifi
Description
GPX4 inhibition enhances glioma radiosensitivity by inducing oxidative stress-dependent SSG and degradation of transglutaminase 2 (TGM2), impairing DNA repair 126

The antioxidant response genes activated by NRF2 include genes responsible for (a) regulating GSH synthesis and metabolism, (b) antioxidant proteins like GPX, (c) drug-metabolizing enzymes and xenobiotic transporters, and (d) additional stress response proteins (Jaramillo and Zhang, 2013)
Fornari F, Gurski RR, Navarini D, Thiesen V, Mestriner LH, Madalosso CA

The antioxidant is associated with a host of health benefits, and has the power to: Increase your energy Detoxify the body Improve the immune system Help neurological diseases, such as Parkinsons Remove toxins from the body and restore cellular health

While weight loss is often linked to a negative impact on PD severity [181], another study suggests that PD progression is faster in patients with metabolic syndrome [182]
