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Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses: A Phase 2 Randomized Clinical Trial

Digital biomonitoring programs, such as wearable heavy metal sensors and smartphone-based pesticide tracking applications, have successfully demonstrated real-time exposure assessment in rural and industrial communities, providing actionable data for both public health authorities and individuals [372,373,374]

Introduction Urinary tract infections (UTIs) are a common and significant health concern worldwide, affecting over 150 million individuals each year [1]

In the gut, the specific Siglec-8 ligand distribution is less characterized, but colonic mucus and epithelial glycocalyx are rich in sialylated and sulfated glycans that could serve as ligands (189)

Notably, p53 was upregulated in PMB-treated mice and HK-2 cells
