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Since it is suggested that p53, p16, p21 are directly related to the induction of senescence in chondrocytes ( IL-6 and -8 , which however were not detectable due to the low expression level
J Pharmacol Exp Ther (2002) 301(2):41826
FIGURE 2 The structural hallmark of IDD is the progressive dehydration of the NP mainly due to the gradual loss of proteoglycans within the ECM (Vadal et al., 2015
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View Full Study Characterization of 0839 - A tool compound for pre-clinical mode-of-action studies of amylin analogues such as cagrilintide
