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[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Wallace D.C

Thus, taking large doses of caffeine in conjunction with ED abuse may be associated with a risk of convulsant effects, mostly in patients who take bupropion or tricyclic antidepressants

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this was illustrated in a population-based study with diabetes that demonstrated carnitines potentially are associated with the pathogenesis of insulin resistance caused by mitochondrial stress, including incomplete fatty acid oxidation and mitochondrial lipid overload 18

doi: 10.1371/journal.pone.0188123 84 SoleimanisardooLRouhaniMSardooFSGozashtiMH