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10.1152/ajpgi.00081.2017 [DOI] [PMC free article] [PubMed] [Google Scholar]

IRP-2 inactivation requires translation of another protein

Herviou L, Jourdan M, Martinez AM, Cavalli G, Moreaux J
Fatty acids with a higher number of double bonds are more susceptible to this process, as the removal of hydrogen atoms becomes easier with increased unsaturation

This is a hard ceiling, not an estimate
