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A clinical trial in Shanghai Pulmonary Hospital showed HRS-4642 treatment led to objective responses in 2 of 9 KRAS G12D-driven NSCLC patients [169, 170]

Impaired re-esterification of DAG by acyltransferases could result in a normalized release of FA generated from the hydrolysis of TAG

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Bannasch P., Zerban H

[DOI] [PubMed] [Google Scholar] 3.CDC
