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FIGURE 1 FIGURE 2 Platinum-Based Compounds The first antitumoral agent of this group was cisplatin, patented in 1978 for the treatment of different types of solid tumors

Zhang, X.G., Li, H., Wang, L., Hao, Y.Y., Liang, G.D., Ma, Y.H., Yang, G.S

Handle according to laboratory safety protocols and institutional research guidelines

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In 2002, we compared the effect of the use of NEM with that of other commonly used alkylating agents and reported that both iodoacetic acid and monobromobimane slowly react with SH groups yielding too high values of GSSG