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Further studies based on the regulation of xCT expression, ROS stress and redox homeostasis, and energy stress caused by specific nutrient addiction or deficiency will increase the clinical importance of ferroptosis modulation as an effective therapeutic strategy for ovarian cancer

Although it has been demonstrated that Epitalon exerts, among other effects, a direct influence on melatonin synthesis, alters the mRNA levels of interleukin-2, modulates the mitogenic activity of murine thymocytes, and enhances the activity of various enzymes, including AChE, BuChE, and telomerase, it remains uncertain whether these are the sole mechanisms of action of this compound

When examining SHBG levels, all studies contributed except for Jensterle et al

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