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The likelihood ratio based on the objective function value was used to test different hypotheses regarding the structure of the variancecovariance matrix for inter-individual variability and residual variability models, and to assess the covariate effects on toxicokinetic parameters

These medications may be dispensed by state-licensed 503A compounding pharmacies as part of personalized care

To mitigate this undesirable symptoms in TMAU patients, we considered restoring the FMO3 gene's functionality

Verlaet AAJ, Maasakkers CM, Hermans N, Savelkoul HFJ
Acknowledgements This work is supported by the Propionic Acidemia Foundation award to G.F.Z., NIH R01 AA030026 to X.C