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It includes some heartburn medicines including proton pump inhibitors (PPIs) such as esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole, H2 blockers such as famotidine and certain diabetes medicines such as metformin

In addition, the anti-tumor activity is due to ADCC, whereby Ab-coated tumor cells are lysed by NK cells [67]

not FDA-approved

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Systemic side effects are rare but can include mild diarrhea, anxiety, or heart palpitations