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Description
TMAO potentially affects carbohydrate, TAG and cholesterol metabolism by influencing the total bile acid pool size through the reduction of bile acid production via the suppression of the crucial enzymes CYP1A1 and CYP27A1, as well as by restricting bile acid enterohepatic circulation through the repression of the organic anion transporter and the expression of the multidrug resistance protein family (Reference Song and Malhi24)

It is important that patients tell the care team if they are sexually active, pregnant, or breastfeeding

J Clin Endocrinol Metab 106(7):e2622-e32 2021 PMC8502447 Kursan S, McMillen TS, Beesetty P, Dias-Junior E, Almutairi MM, Sajib AA, Kozak JA, Aguilar-Bryan L, Di Fulvio M

The involvement of MEF2C in Rett syndrome was first reported in 2008 (159)

Main indications : cutting, weight loss, athletic performance (endurance and strength), post-workout muscle recovery, reduction of muscle soreness
