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The LRRK2 mutations impair synaptic vesicle endocytosis, leading to alterations of DA metabolism and DA-mediated toxic effects in dopaminergic neurons derived from iPSCs generated from reprogrammed PD patient fibroblasts carrying LRRK2 mutations [132]
In this phase, the liver attaches a glutathione molecule to a toxin, making it water-soluble so the body can easily flush it out
Meta-analysis: hoarding symptoms associated with poor treatment outcome in obsessive-compulsive disorder
K., Yadav, S., Berrocoso, J
Media References 01 Ah Mew N, Loewenstein JB, Kadom N, et al
