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The relative infrequency of studies undertaken within the Valley of Death DRLs 46 can hinder the development of ITD system designs across the full design arc from conceptualization (DRL-1) to real-word deployment (DRL-9)

Cox GM, Harrison TS, McDade HC, et al

The (S)-(-) isomer of ALA is produced synthetically, while only the (R)-(+)-enantiomer is found in nature [131]

To extract pigments from the samples, 1-mL aliquots of the inoculated cell culture were pelleted through centrifugation and re-suspended in dimethyl sulfoxide (DMSO)

AT1R blockers, such as losartan, have been investigated for their potential to mitigate BBB damage (Huang and Zhang, 2024)