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Its potent stimulatory effect on gonadotropin secretion facilitates ovulation and contributes to fertility management strategies

doi: 10.1111/dom.14775

One of the most significant reproductive hormones in females is estrogen, produced primarily in the ovaries

When administered together, their mechanisms converge to amplify appetite regulation, energy intake reduction, and glycemic improvements, exceeding the individual effects of monotherapy by acting on complementary neuroendocrine circuits regulating body weight and metabolism 1-3
