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PMID: 32720683 Chang M, Russo GS, Canseco JA, Nicholson K, Sharma R, Koomson J, Vaccaro A.R

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Single-cell chromatin modification profiling reveals increased epigenetic variations with aging

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These findings are consistent with those for other antioxidant enzymes: for example, lack of peroxiredoxin 3, a mitochondrially localized antioxidant enzyme, also augments apoptotic signaling in some cell types (60)