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[DOI] [PubMed] [Google Scholar] 51.Ramrez-Garza S.L., Laveriano-Santos E.P., Marhuenda-Muoz M., Storniolo C.E., Tresserra-Rimbau A., Vallverd-Queralt A., Lamuela-Ravents R.M

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One significant positive in this study is that they also used laser Doppler scanning (recovery of blood flow in the ischemic muscle) to indicate the promotion of angiogenesis alongside Western blot and real-time PCR for the expression of VEGFR2

For this reason, it is generally recommended that the therapeutic regimen be kept as simple as possible, since the risk of adverse effects is lower when one or two agents are given at higher doses as compared to a multiple-drug regimen using lower doses